It’s important to remember that not everyone reacts the exact same way to the same stimuli, especially when you’re talking about things consumed in the body.
For instance, most people who take Benadryl, or diphenhydramine, experience a sedating side effect from the antihistamine.
Further, it is now sold as an OTC sleep aid if you don’t want to pay more money for something like melatonin. I was using it for insomnia when I was a kid, long before it was sold for the purpose in major stores. Despite diphenhydramine’s near universally accepted classification as a sedative, I had a friend in college who swore that she would get hyper whenever she consumed the medication. Even the most honest person could randomly lie for any number of reasons, but she was also the smartest friend of the bunch. I just have to chalk it up to substances affecting human minds differently with each person. You can’t assume the same medicine is going to give two different people the exact same effects. This is also true with THC, regardless of what you might mistakenly assume. For instance, not all people actually experience noticeable effects when they consume cannabis edibles. That’s because some livers are just really bad at metabolizing THC, therefore the person with the liver will probably never experience serious effects from cannabis edibles. I’m definitely one of those people, while my sister absolutely loves cannabis edibles by contrast. Cannabis edibles are her favorite cannabis products when she’s given a choice at her select cannabis dispensaries in her city. I buy cannabis inhalation products instead, like cannabis concentrates and flower products.